+100%-
Utkal University
Bhubaneswar, Odisha
ଉତ୍କଳ ବିଶ୍ୱବିଦ୍ୟାଳୟ
ଭୁବନେଶ୍ୱର, ଓଡ଼ିଶା
Dr. Jyotsnarani Pradhan
Name: Dr. Jyotsnarani Pradhan
Designation: Assistant Professor (Stage-III)
Qualification: Ph.D.
Phone No.: 9853411916
ORCID: https://orcid.org/0000-0002-6490-9729
E-mail ID: jyotsna.biotech@utkaluniversity.ac.in
Biosketch
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Redox Biology, Phytochemicals and Natural Products, Proteomics, Biochemistry, Molecular Biology, Chronobiology and Neuroendocrinology.

Utkal University 2007 – 2012 Ph.D.
Department: Biotechnology
Thesis Title:Screening, isolation and characterization of antioxidant compounds from seaweeds of Chilika Lake”
Areas: Environmental Biotechnology
Advisor: Prof. S.P. Adhikary and Dr. Luna Samanta
Utkal University 2003 – 2005 M.Sc.in Biotechnology
Department: Biotechnology
Sambalpur University 1999 – 2002 Bachelor of Science
Department: Zoology
Hons:Zoology
Utkal University (2024- continuing)present Assistant Professor Stage-III
Utkal University 2019-2024 Assistant Professor (Stage-II)
Utkal University February. 2015- February. 2019 Assistant Professor (Stage-I)
Institute of Life Sciences, Bhubaneswar
Designation: DBT-Research Associates
Topics: ‘Development of scaffold based 3D glioblastoma tumor model for in vitro assessment of anticancer drugs loaded in nanoparticles for better therapeutic efficacy’
2011-2013
Tectona Biotech, Bhubaneswar
Designation: BCIL Trainee
Topics: “Plant tissue culture: Application and practice of in vitro response to hybrid plantlets multiple auxiliary shoot proliferation of banana Musa paradisiaca”
Dec, 2006-June, 2007
Programme / Course Department Responsibilities Duration
M.Sc. Biotechnology
Biochemistry (BTC-101), Cell Biology (BTC-102), Molecular Biology (BTC-203),
Animal Biotechnology (BTC-204), Genetic Engineering (BTC-301), and
Biotechniques (BTC-304)
Department of Biotechnology, Utkal University Delivering lectures and tutorials, conducting practical sessions,
conducting seminars, holding student consultation hours, assessing
academic performance, and evaluating assignments and examinations.
2015 – Continuing
M.Phil. and Ph.D. Biotechnology
Tools and Techniques in Biotechnology
Department of Biotechnology, Utkal University Delivering lectures, conducting seminars, mentoring research scholars,
evaluating presentations, assessing academic performance, and evaluating
coursework and examinations.
2017 – Continuing
M.Sc. Biotechnology
Practicals Based on Theory Papers
Department of Biotechnology, Utkal University Conducting and supervising laboratory practicals associated with theory
papers, providing hands-on training in biotechnology techniques, and
evaluating practical examinations.
2015 – Continuing
  • Chakraborty D, Behera S, Naik N, Nial PS, Pradhan KC, Subudhi U, Dandapat J, Pal S, Pradhan J. Organometallic Iridium (III) complex interacts with DNA and exhibits anticancer potential: Insights from biophysical, cell-based and computational studies. Biochemical and Biophysical Research Communications. 2026 May 10:153920.
  • Sahoo S, Bhol NK, Kanungo N, Majhi S, Pradhan J, Dandapat J. Artificial Intelligence in Bio-Recovery of Noble Metals: A Sustainable Strategy for Circular Economy. Int J Bioinfor Intell Comput. 2025 Aug;4(2):101.
  • Behera S, Pradhan KC, Barik S, Sarkar M, Kumar J, Dandapat J, Pradhan J, Pal S. Anticancer efficacy of bis-heteroleptic iridium (III) complexes with difluoro-substituted phenylpyridine ligands. RSC Advances. 2025;15(28):22875-88.
  • Behera D, Pattnaik SS, Patra SS, Barick AK, Pradhan J, Behera AK. Development and characterization of water hyacinth reinforced thermoplastic starch as sustainable biocomposites. RSC Sustainability. 2025;3(4):1807-18.
  • Das P, Das M, Sahoo SK, Dandapat J, Pradhan J. Characterization of extracellular chitin deacetylase from Aneurinibacillus aneurinilyticus isolated from marine crustacean shell. Current Research in Microbial Sciences. 2025 Jan 1;8:100325.
  • Behera AK, Pattnaik SS, Mohanty C, Srivastav R, Pradhan J. Mechanical and cytotoxic analysis of cutlery developed from phenol‐formaldehyde modified soy‐jute composite. Vietnam Journal of Chemistry. 2024 Apr;62(2):151-9.
  • Jema JP, Pradhan J, Chainy GBN, Hati AK, Nayak D, Kausik, S, Dandapat J. Covid 19 Cases and Co-Morbidities: Complementary and Alternative Medicinal Systems (CAM) For Integrated Management of the Pandemic. Journal of Herbal Medicine. 23 August 2023, 100745. https://doi.org/10.1016/j.hermed.2023.100745.
  • Nayak M, Das D, Pradhan J, Ahmed RG, Laureano-Melo R, Dandapat J. Epigenetic signature in neural plasticity: the journey so far and journey ahead. Heliyon. 2022 Dec 19:e12292.
  • Rath S, Chakraborty D, Pradhan J, Khan MI, Dandapat J. Epigenomic interplay in tumor heterogeneity: Potential of epidrugs as adjunct therapy. Cytokine. 2022 Sep 1;157:155967.
  • Jena AB, Samal RR, Kumari K, Pradhan J, Chainy GB, Subudhi U, Pal S, Dandapat J. The benzene metabolite p-benzoquinone inhibits the catalytic activity of bovine liver catalase: A biophysical study. International Journal of Biological Macromolecules. 2021 Jan 15;167:871-80.
  • Mohanty C, Pradhan J. A human epidermal growth factor-curcumin bandage bioconjugate loaded with mesenchymal stem cell for in vivo diabetic wound healing. Materials Science and Engineering: C. 2020 Jun 1;111:110751.
  • Pradhan J, Mohanty C, Sahoo SK. Protective efficacy of crocetin and its nanoformulation against cyclosporine A-mediated toxicity in human embryonic kidney cells. Life Sciences. 2019 Jan 1;216:39-48.
  • Bunker SK, Dutta A, Pradhan J, Dandapat J, Chainy GB. Curcumin restores hepatic epigenetic changes in propylthiouracil (PTU) Induced hypothyroid male rats: A study on DNMTs, MBDs, GADD45a, C/EBP-β and PCNA. Food and Chemical Toxicology. 2019 Jan 1;123:169-80.
  • Sahu S, Dutta A, Ray DK, Pradhan J, Dandapat J. Host plant-derived allelochemicals and metal components are associated with oxidative predominance and antioxidant plasticity in the larval tissues of silkworm, Antheraea mylitta: Further evidence of joint effects hypothesis. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 2018 Sep 1;223:39-49.
  • Rautray P, Pradhan J, Samanta L, Antioxidant and hepatoprotective properties of macroalga Chaetomorpha linum against experimentally induced oxidative stress, 2016, International Journal of Recent Scientific Research 7, 7, 12688-12691.

Book Chapter

  • Ganguly B, Hota M, Pradhan J. Skin aging: implications of UV radiation, reactive oxygen species and natural antioxidants. London, UK: Intech Open; 2021 Sep 19.

Research Guidance

Ph.D. Guidance
  • Ms. Poonam Das, Ph.D. (Guide) (Regd. No.: 01-Biotechnology 2020-2021; Utkal University) – Topic: Molecular Cloning and Characterization of a Novel Microbial Chitin Deacetylase in Improved Production of Chitosan with Bio Adsorption Efficiency. (Thesis Submitted)
  • Ms. Jyoti Prava Jema, Ph.D. (Co-Guide) (Regd. No.: 04-Biotechnology 2023-2024) – Topic: Impact of homeopathic drug, Thyroidinum and Arsenic album on hypothyroidism-associated redox imbalance and Epigenetic alteration in the liver and brain of Wistar rat. (Continuing)
  • Ms. Sonali Das, Ph.D. (Guide) (Regd. No.: 01-Biotechnology-2025-26; Utkal University) – Topic: Plasticizer Induced Neurodegeneration: Insights into Molecular Mechanism and Therapeutic Intervention. (Continuing)
  • Ms. Sangita Subhadarshini, Ph.D. (Guide) – Doing Ph.D. Coursework.
  • Ms. Sneha, Ph.D. (Guide) – Doing Ph.D. Coursework.
Post-Doctoral Guidance
  • Dr. Aradhana Mohanty, RUSA-PDF, Utkal University, Bhubaneswar, Odisha.
M.Phil. Guidance
  • Ms. Manisha Hota, M.Phil. (Utkal University) – Topic: Isolation, characterization and screening of bioactive compounds with UV protective and antioxidant potential from Gracilaria verrucosa of Chilika Lake. (Awarded)
  • Ms. Bristy Ganguly, M.Phil. (Utkal University) – Topic: Evaluation of antioxidant activity of extract prepared from red algae Gracilaria verrucosa in lipopolysaccharide stimulated RAW 264.7 macrophages. 2021. (Awarded)
M.Sc. Project / Dissertation
  • 49 Nos.
Summer Training
  • 05 Nos.

Research Projects

  • Collaborative Research Project Grant in Biotechnology, “Understanding the molecular mechanism of anti-thyroid drug (propylthiouracil)-induced redox imbalance and epigenetic alteration” funded by DST Govt. of Odisha, (Co-PI) (2023-2026) (On going).
  • Project entitled “Signature of redox regulatory proteins, transcription factors and Biological clock genes in hypothyroid rat: impact of Time Restricted Feeding (TRF) and curcurnin” funded by DST, Govt. of Odisha. (PI) (2022-2025) (On going).
  • Project entitled “Evaluation of anti-inflammatory and Immunomodulatory potential of red alga Gracilaria verrucosa” funded by WB-OHEPEE Program, Utkal University, Odisha, (PI) (2022-2023) (Completed).
  • Project entitled “Efficacy of homoeopathic medicines (30 c) on propylthiouracil (PTU)-induced hypothyroid rat” funded by AYUSH, Govt. of India (Co-PI) (2019-2023) (Completed).
  • Project entitled “Isolation, characterization and screening of bioactive compounds with UV protective and antioxidant potential from the Red alga, Gracilaria verrucosa of Chilika Lake” funded by Odisha University Research and Innovation Incentivisation Plan (OURIIP) Seed Grant, Odisha State Higher Education Council, Govt. of Odisha (PI) (2020-2022) (Completed).
  • Project entitled “Signature of DNA methylation machinery in the brain of propyl thiouracil (PTU)-induced hypothyroid rat: Effect of green tea catechins” funded by DST, Govt. of Odisha (Co-PI) (2018-2021) (Completed).
  • Project entitled “Modified assay procedure for the estimation of hydrogen peroxide in Biological samples using microwell reader”, funded by Utkal University research grant (PI) (2017-2019) (Completed).

Conference and Symposium

  • Participated and presented a paper title “Assessment of antioxidant, UV-protective and anti-inflammatory activities of hydroalcoholic extract of Gracilaria verrucosa” at International conference on Recent Trends in Biotechnology for better tomorrow, 25-26th March 2025 organized by Department of Biotechnology, Maharaja Sri Ram Chandra Bhanja Deo University, Baripada, Odisha.
  • Participated and presented a paper title “Impact of Time-Restricted Feeding on Redox Imbalance in PTU-Induced Hypothyroid Rat Liver” at International Conference on Developments in the Science of Oxidative Stress and Redox Medicine (SFRR-INDIA-DISCOVER-2024), 6-9th November 2024 organized by BARC, Mumbai.
  • Participated in one day National Symposium and workshop on Clinical Proteomics (NSWCP-2024) held at Institute of Life Sciences, Bhubaneswar on 20th August 2024.
  • Participated in the First Symposium of the Quarterly Union of Academic Disclourse 2024, Bhubaneswar, Odisha Organized by School of Biological Sciences, NISER, Bhubaneswar and Institute of Life Sciences, Bhubaneswar on 27th January 2024.
  • Participated and presented a paper “Lead acetate-induced conformational changes in bovine liver catalase: A comprehensive assessment using biophysical, biochemical, and cell-based approaches” at Odisha Research Scholar Conclave 2023, (ORC 2023) jointly organised by OSHEC and Sambalpur University, Sambalpur during 14-16 November 2023.
  • Participated in the International Conference on Technological Innovation in Animal Science Research and Social Transformation, sponsored by SERB-India, World Bank-OHEPEE, ZSI organized by Department of Zoology, Utkal University, Bhubaneswar, Odisha, India, held from 24th-26th February, 2023.
  • Participated in the DAE-BRNS Outreach Theme Meeting on ‘Societal Applications of Nuclear Science and Technology,’ organized by the Bhabha Atomic Research Centre (BARC), Board of Research in Nuclear Sciences (BRNS), Institute of Physics Bhubaneswar, NISER Bhubaneswar, and MSCBD University Baripada, in association with the Indian Association of Nuclear Chemists and Allied Scientists (IANCAS), held from March 25th to 27th, 2022.
  • Participated and presented paper on” Spectroscopic and Biophysical Interaction Studies of novel Ir(F2ppy)2 N hydroxypiconilamide complex with calf thymus DNA for its potential Application in cancer research” at 36th Annual Conference of Orissa Chemical Society and National conference on Advances in Materials Chemistry and Applications (OCS-AMCA-2022) organized by Department of Chemistry, Utkal University, Bhubaneswar during December 18-19, 2022.
  • Participated and presented paper on “Assessment of anti-inflammatory, antioxidant and photoprotective activities of hydroalcoholic extract of Gracilaria verrucosa” at Odisha Research Scholar Conclave 2022, (ORC 2022) jointly organised by OSHEC and Ravenshaw University Cuttack during 14-16 November 2022.
  • Participated and presented paper on “Phytochemical analysis and evaluation of antioxidant and photoprotective activities of Gracilaria verrucosa extract against UV-induced oxidative damage in fibroblast cells” at Odisha Research Scholar Conclave 2021, (ORC 2021) jointly organised by OSHEC and Utkal University Bhubaneswar during 13-15 November 2021.
  • Participated and paper submitted “Antioxidant and photoprotective activity of ethanolic extract of Gracilaria verrucosa against UVB-induced oxidative damages in 3T3 fibroblast cells” in the International Conference on Emerging Trends in Biotechnology (ICETB) organized by School of Bio Sciences and Technology, Vellore Institute of Technology along with Association of Biotechnology and Pharmacy, from December 14-16, 2020.
  • Participated and paper submitted “Attenuation of UVB-induced oxidative damages in 3T3 fibroblast cells by ethanolic extract of red alga Gracilaria verrucosa” in the International Virtual Conference, Emerging Frontiers in Healthcare and Delivery (EFHD-2020), held on September 12-14, 2020, organized by Department of Biology, School of Applied Science at Kalinga Institute of Industrial Technology (KIIT) Deemed to be University, Bhubaneswar, Odisha, India.
  • Paper Presented on “Antioxidant and Photoprotective Properties of Mycosporine Like Amino Acids from Red Alga, Gracilaria verrucosa of Chilika Lake” at 17th Annual Meeting of the Society for Free Radical Research India (SFRR-INDIA-2020) & International Conference on “Role and Management of Oxidative Stress in Human Disease” organized by Society For Free Radical Research-India & Bhabha Atomic Research Centre, Mumbai on February 12-15, 2020.
  • Paper Presented on ‘Antioxidative and UV protective potential of red alga Gracilaria verrucosa from Chilika lake’ at National Conference on Recent Advances in Energy, Environment and Health Sciences (RAEEHS-2019) organized by Department of Chemistry, ITER, Siksha‘O’Anusandhan, Deemed to be university, Bhubaneswar, Odisha on October 18-19, 2019.
  • Participated in National Seminar cum Workshop on “Proteomics in Public Health”, sponsored by World Bank-Odisha Higher Education Program for Excellence and Equity, organized by P.G. Department of Biotechnology, Utkal University, Bhubaneswar, Odisha. 15th and 16th March, 2019.
  • Paper Presented on “A sensitive microplate-based method for the estimation of hydrogen peroxide in biological sample by mFOX Reagent” at National seminar on Future India: Science & Technology jointly organized by Indian Science Congress Association (ISCA) Bhubaneswar Chapter and KIIT Deemed to be University and KISS Deemed to be University, Bhubaneswar on 1st-2nd February, 2019.
  • Paper presented on “A sensitive microplate-based method for the determination of Hydrogen peroxide in biological samples by mFOX reagent” at National Seminar on Recent Trends in Microbiology and Biotechnology organized by Department of Biotechnology, MITS School of Biotechnology and Society of Biotechnology and Bioinformatics Bhubaneswar, Odisha. 16th and 17th March, 2018.
  • Paper presented on “Optimization of Hydrogen Peroxide Determination in Biological samples Using Ammonium ferrous sulfate and Xylenol orange Reagent” at 85th Annual Session of National Academy of Sciences, India (NASI) & Symposium on Marine and Freshwater Ecosystem for National Development, KIIT, Bhubaneswar, Odisha, 6th – 8th December 2015.

Workshop Attended

  • Participated in five days’ workshop on “National Workshop on Laboratory Animal Handling, Experimental Procedures, and In-Vivo Imaging” from 7th – 11th January’ 2025 at Institute of Life Sciences, Bhubaneswar.
  • Participated in three days’ workshop on “National Symposium and workshop on Clinical Proteomics (NSWCP-2024)” held at Institute of Life Sciences, Bhubaneswar from 21st – 23rd August 2024.
  • Participated in Two days DST-SERB Sponsored Workshop on “Basic Gene cloning and Transgenic” Techniques at National Institute of Technology, Rourkela, from 24th -25th February, 2024.
  • Participated in Two days’ workshop on Recombinant Protein purification and protein Crystallography 20-21 October, 2022, organized by Institute of Life Sciences, Bhubaneswar.
  • Participated in 3 weeks online hands-on workshop on Course 1: Target Development, Course 2: Drug Development, Course 3: Drug Screening organized jointly by Crescent Innovation & Incubation Council (CIIC), Chennai & Hains Biosolutions, Chennai Dt. 20-22 May, 2021, 27-29 May, 2021 & 3-5 June, 2021.
  • Participated in Department of Science and Technology sponsored 2-weeks workshop on “Basic and Advanced Proteomics Approaches” organized by IIT Bombay from 15‐26 February 2021.
  • Participated in virtual workshop on “Sars-CoV-2 Diagnosis By Real-time PCR” organised jointly by Immugenix Biosciences (IGB), Chennai & Crescent Innovation & Incubation Council (CIIC), Chennai on 30th May 2020.
  • Participated in virtual hands-on workshop on Primer and Probe Designing held on 27th-May 2020 at ImmuGenix Biosciences Pvt. Ltd., Chennai.
  • Participated in the Live Workshop entitled “Foldscope Microscope – Sample Preparation and Digital Documentation” on 25.08.2020, organized by Centre for Molecular and Nano Medical Sciences, Sathyabhama Institute of Science and Technology, Chennai.
  • Participated in hands-on training workshop on “Basic Cell Culture Technology” from October 22nd – 25th, 2019, at National Center for Cell Science (NCCS), Pune, India.
  • Participated in DBT sponsored workshop on “Cloning and identification of abiotic stress-induced gene” held at Institute of Life Science, Bhubaneswar from 11th -15th March 2008.
  • DBT- Research Associateship
  • Utkal University Seed grant.
  • Odisha University Research and Innovation Incentivisation Plan (OURIIP) Seed Grant.
  • Got 1st prize in Poster presentation at Odisha Research Scholar Conclave-2021

Administrative Responsibilities

  • Coordinator, Department of Biotechnology, Utkal University (May 2025 – March 2026)
  • Admission In-charge for Master of Science in Biotechnology and Doctor of Philosophy in Biotechnology programmes, Utkal University (Since 2015)
  • Co-Coordinator, Rashtriya Uchchatar Shiksha Abhiyan 2.0 Centre of Excellence on Environment, Climate Change and Public Health (2020–2023)
  • Centre Superintendent for conducting Master of Science in Biotechnology examinations, Utkal University (Since 2020)
  • Member, Departmental Research Committee, Department of Biotechnology, Utkal University (Since 2017)
  • Officer on Special Duty, Centre of Innovation and Incubation, Utkal University, Bhubaneswar (Since April 2026)

Patents

  • Indian Patent Number: 560356
    Title of Invention: PROCESS FOR DEVELOPING SEAWEED EXTRACT AND COMPOSITION USEFUL AGAINST UV-RADIATION, OXIDATIVE DAMAGE AND SKIN CANCER
    Name and Address of Patentee(s):

    • Prof. Luna Samanta, Department of Zoology, Ravenshaw University, Cuttack – 753003, India.
    • Dr. Soumya Ranjan Jena, Department of Zoology, Ravenshaw University, Cuttack – 753003, India.
    • Dr. Jyotsnarani Pradhan, Department of Biotechnology, Utkal University, Vani Vihar, Bhubaneswar – 751004, India.
    • Prof. Siba Prasad Adhikary, Department of Biotechnology, Utkal University, Vani Vihar, Bhubaneswar – 751004, India.

    Date of Filing: 15/07/2021
    Publication Date: 25/11/2022
    Granted Date: 14/02/2025

  • Australian Innovative Patent Number: 2021104442
    Title of Invention: PROCESS FOR DEVELOPING SEAWEED EXTRACT AND COMPOSITION USEFUL AGAINST UV RADIATION, OXIDATIVE DAMAGE AND SKIN CANCER
    Name and Address of Patentee(s):

    • Prof. Luna Samanta, Department of Zoology, Ravenshaw University, Cuttack – 753003, Odisha.
    • Dr. Soumya Ranjan Jena, Department of Zoology, Ravenshaw University, Cuttack – 753003, Odisha.
    • Dr. Jyotsnarani Pradhan, Department of Biotechnology, Utkal University, Vani Vihar, Bhubaneswar – 751004, India.
    • Prof. Siba Prasad Adhikary, Department of Biotechnology, Utkal University, Vani Vihar, Bhubaneswar – 751004, India.

    Date of Filing: 22/07/2021
    Grant Date: 30/03/2022

Professional Membership

  • Life member of Society of Free Radical Research (SFFR), India.
  • Life member of Proteomics Society of India (PSI).
  • Life member of Indian Science Congress Association (ISCA).
  • Life member of Association of Gerontology (INDIA).
  • Life member of Indian Gerontological Association (IGA).
  • Life member of Odisha Bigyan Academy (OBA).

Reviewer / Editorial Board

  • Reviewer, Frontiers in Pharmacology.
  • Reviewer, Current Research in Microbial Sciences, Elsevier Publisher.
  • Reviewer, Frontiers in Microbiology.