Prof. Jagneshwar Dandapat

PhD thesis

• JAGNESHWAR DANDAPAT, “ANTIOXIDANT DEFENCE SYSTEM AND PRAWN”.:Name of the DRC (chairperson), Name of the Advisor -Prof. G.B.N Chainy (Guide), Utkal University.

Book Articles (Authored/Edited)

1. Srikanta Jena, Suresh K. Bunker, Jagneshwar Dandapat and G.B.N. Chainy ¨ Age-Related Changes in Antioxidant Enzymes of Rat Kidney and Oxidative Stress Parameters with Special Reference to Methylation of the Catalase Promoter. Springer Science+Business Media Singapore,DOI 10.1007/978-981-10-2155-8_9. 2016.

Journal Articles

• Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin

Manas K Jagdev, Dharma R Tompa, Losee L Ling, Aaron J Peoples, Jagneshwar Dandapat, Chinmayee Mohapatra, Kim Lewis, Dileep Vasudevan. International Journal of Biological Macromolecules(2023) https://doi.org/10.1016/j.ijbiomac.2023.126771

• Covid 19 Cases and Co-Morbidities: Complementary and Alternative Medicinal Systems (CAM) For Integrated Management of the Pandemic.

Jema JP, Pradhan J, Chainy GBN, Hati AK, Nayak D, Kausik, S, Dandapat J.  Journal of Herbal Medicine.  23 August 2023, 100745. https://doi.org/10.1016/j.hermed.2023.100745. (IF: 2.542)

• The ameliorative effect of Piper trioicumin attenuating cognitive deficit in scopolamine induced neurotoxicity in experimental rats.

Umesh Chandra Dash, Sandeep Kumar Swain, Atala Bihari Jena, Jagneshwar Dandapat, Atish Kumar Sahoo. Journal of Ethnopharmacology(2023) https://doi.org/10.1016/j.jep.2023.116911

• Thermodynamics of benzoquinone-induced conformational changes in nucleic acids and human serum albumin.

Atala B. Jena, Rashmi R. Samal, Jagneshwar Dandapat, Umakanta Subudhi. Chemico-Biological Interactions(2023) https://doi.org/10.1016/j.cbi.2022.110281

• Epigenetic signature in neural plasticity: the journey so far and journey ahead.

Madhusmita Nayak, Diptimayee Das, Jyotsnarani Pradhan, RG Ahmed, Roberto Laureano-Melo, Jagneshwar Dandapat, Heliyon, Elsevier, 2022. https://doi.org/10.1016/j.heliyon.2022.e12292

• A Computational Insight on the Inhibitory Potential of 8‐Hydroxydihydrosanguinarine (8‐HDS), a Pyridone Containing Analog of Sanguinarine, against SARS CoV2.

Atala Bihari Jena, Namrata Kanungo, Gagan Bihari Nityananda Chainy, Vinod Devaraji, Sudipta Kumar Das, Jagneshwar Dandapat, Chemistry & Biodiversity, 2022. https://doi.org/10.1002/cbdv.202200266

• Epigenomic interplay in tumor heterogeneity: Potential of epidrugs as adjunct therapy.

Suvasmita Rath, Diptesh Chakraborty, Jyotsnarani Pradhan, Mohammad Imran Khan, Jagneshwar Dandapat. Cytokine, 2022. https://doi.org/10.1016/j.cyto.2022.155967

• Molecular interaction of benzo-a-pyrene inhibits the catalytic activity of catalase: Insights from biophysical and computational studies.

AB Jena, S Rath, U Subudhi, J Dandapat. Journal of Molecular Structure, Volume 1265, 5 October 2022, 133494. https://doi.org/10.1016/j.molstruc.2022.133494

• CTK7A, a curcumin derivative, can be a potential candidate for targeting HIF-1α/p300 complex: Evidences from in vitro and computational studies.

S Rath, AB Jena, A Bhattacharyya, J Dandapat – Biophysical Chemistry, Volume 287, August 2022, 106828. https://doi.org/10.1016/j.bpc.2022.106828

• Comprehending the role of homeopathic preparations of Rauwolfia serpentinaon oxidative stress parameters of cardiac tissue of DOCA-salt induced hypertensive male rats: An experimental approach.

Sandeep Kumar, Gagan Bihari Nityananda Chainy, Jagneshwar Dandapat, Akshaya Kumar Hati, Laxmikanta Nanda. Phytomedicine Plus, 1(4), 100115. doi: 10.1016/j.phyplu.2021.100115

• Interface-based design of the favipiravir-binding site in SARS-CoV-2 RNA-dependent RNA polymerase reveals mutations conferring resistance to chain termination.

Aditya K Padhi, Jagneshwar Dandapat, Prakash Saudagar, Vladimir N Uversky, Timir Tripathi.  FEBS Letters.  doi:10.1002/1873-3468.14182

• The modulatory role of prime identified compounds in Geophila repens in mitigating scopolamine-induced neurotoxicity in experimental rats of Alzheimer’s disease via attenuation of cholinesterase, β-secretase, MAPt levels and inhibition of oxidative stress imparts inflammation.

Umesh Chandra Dash, Sandeep Kumar Swain, Satish Kanhar, Purusottam Banjare, Partha Pratim Roy, Jagneshwar Dandapat, Atish Kumar Sahoo. Journal of Ethnopharmacology. doi: 10.1016/j.jep.2021.114637

• Factors regulating dynamics of angiotensin-converting enzyme-2 (ACE2), the gateway of SARS-CoV-2: Epigenetic modifications and therapeutic interventions by epidrugs.

Suvasmita Rath, Venkateswarlu Perikala, Atala Bihari Jena, Jagneshwar Dandapat. Biomedicine & Pharmacotherapy, 143, 112095. doi:10.1016/j.biopha.2021.112095

• TLR2 dimer‐specific ligands selectively activate Protein Kinase C isoforms in Leishmania infection.

Arkajyoti Mukherjee, Sayoni Roy, Ashok Patidar, Neelam Bodhale, Jagneshwar Dandapat, Bhaskar Saha, Arup Sarkar.Immunology, 2021.

• A primer on cytokines.

Prashant Chauhan, A Nair, A Patidar, Jagneshwar Dandapat, A Sarkar, B Saha. Cytokine, (2021), 155458, doi: 10.1016/j.cyto.2021.155458

• Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies

Atala B. Jena, Namrata Kanungo, Vinayak Nayak, G.B.N. Chainy and Jagneshwar Dandapat. Scientific Reports, Nature. (2021),11(1),2043. https://doi.org/10.1038/s41598-021-81462-7

• The benzene metabolite p-benzoquinone inhibits the catalytic activity of bovine liver catalase: A biophysical study.

Atala B. Jena, Rashmi R. Samal, Kanchan Kumari, Jyotsnarani Pradhan, Gagan B. N. Chainy, Umakanta Subudhi, Satyanarayan Pal, Jagnehswar Dandapat. International journal of biological macromolecules. (2021) vol. 167: 871-880. doi-:https://doi.org/10.1016/j.ijbiomac.2020.11.044

• Recombinant expression, purification and SAXS analysis of Arabidopsis thaliana ClpC1.

Manas K. Jagdev, Jagneshwar Dandapat, Dileep Vasudevan. International Journal of Biological Macromolecules. (2021) 167, 1273–1280. https://doi.org/10.1016/j.ijbiomac.2020.11.081

• Oxidative stress correlates well with markers of metabolic syndrome in clinically hypothyroid cases: a hospital based study in a remote tribal district.

S Panda, MK Dash, PK Thatoi, Jagneshwar Dandapat. B Rath. RUDN Journal of Medicine,(2021) 25 (1), 55-65

• March of Mycobacterium: miRNAs intercept host cell CD40 signalling.

Prashant Chauhan,  Jagneshwar Dandapat, Arup Sarkar & Bhaskar Saha. Clinical & Translational Immunology. (2020); doi: 10.1002/cti2.1179

• Leaf Extract of Nerium oleander Inhibits Cell Proliferation, Migration and Arrestof Cell Cycle at G2/M Phase in HeLa Cervical Cancer Cell.

Shubhasmita Mohapatra, Anil K. Biswal, Jagnehswar Dandapat & Priya R. Debata. Anti-Cancer Agents in Medicinal Chemistry(2020);http://10.2174/1871520620666200811121400

• Isolation, identification, and quantification of Pentylcurcumene from Geophila repens: A new class of cholinesterase inhibitor for Alzheimer’s disease.

Umesh Chandra Dash, Satish Kanhar, Anshuman Dixit, Jagnehswar Dandapat, Atish Kumar Sahoo. Bioorganic chemistry,(2019) 88, 102947. https://doi.org/10.1016/j.bioorg.2019.102947

• First report on transferrin in the silkworm, Antherae amylitta, with a putative role in antioxidant defense: Insights from proteomic analysis and immunodetection.

Abinash Dutta ,Jagneshwar Dandapat, Nakulananda Mohanty. Comparative Biochemistry and Physiology. (2019); Part B 233: pp. 23-34. https://doi.org/10.1016/j.cbpb.2019.03.010

• Curcumin restores hepatic epigenetic changes in propylthiouracil (PTU) Induced hypothyroid male rats: A study on DNMTs, MBDs, GADD45a, C/EBP-β and PCNA.

Suresh Kumar Bunker, Abinash Dutta, Jyotsnarani Pradhan, Jagneshwar Dandapat & G.B.N. Chainy. Food and Chemical Toxicology (2019); 123. 2019, doi.org/10.1016/j.fct.10.050

• Pro-inflammatory cytokine Interleukin-1β (IL-1β) controls Leishmania infection.

Tejaswini Patil, Vasundhara More, Deepti Rane, Arkajyoti Mukherjee, Rahul Suresh, Ashok P atidar, Neelam Bodhale, David Mosser, Jagneshwar Dandapat, Arup Sarkar. Cytokine (2018);doi.org/10.1016/j.cyto.2018.06.033.

• Neutrophils: Interplay between host defense, cellular metabolism and intracellular infection.

Deepti Rane, Tejaswini Patil, Vasundhara More, Sushree Sangita Patra, Neeelam Bodhale, Jagneswar Dandapat & Arup Sarkar. Cytokine (2018); doi.org/10.1016/j.cyto.2018.07.009.

• Foliar supplementation of ascorbic acid and glycine boost the growth performance and antioxidant protection in the larvae of tropical tasar silkworm, Antheraea mylitta.

Abinash Dutta, Jagneshwar Dandapat & Nakulananda Mohanty. Journal of Entomology and Zoology Studies(2018); E-ISSN: 2320-7078 P-ISSN: 2349-6800, 136-142.

• Type-1 interferons prolong the lifespan of neutrophils by interfering with members of the apoptotic cascade.

Eresso Agaa, Arkajyoti Mukherjee, Deepti Rane, Vasundhara More, Tejaswini Patil, Ger van Zandbergend, Werner Solbach, Jagneswar Dandapat, Heidi Tackenberg, Mareike Ohms, Arup Sarkarb, Tamas Laskay. Cytokine. (2018); doi.org/10.1016/j.cyto.2018.06.027.

• Low H₂O₂ and enhanced oxidative resistance in the diapause-destined pupa of silkworm, Antheraea mylitta (Lepidoptera: Saturniidae) suggest their possible involvement in dormancy and lifespan extension.

Sahoo, A., Dutta, A., Dandapat, J., & Samanta, L. BMC Zoology (2018); DOI: 10.1186/s40850-018-0027-4.

• Host plant-derived allelochemicals and metal components are associated with oxidative predominance and antioxidant plasticity in the larval tissues of silkworm, Antheraea mylitta: Further evidence of joint effects hypothesis.

Smaranika Sahu, Abinash Dutta, Dinesh Kumar Ray, Jyotsnarani Pradhan, Jagneshwar Dandapat. Comparative Biochemistry and Physiology (2018); DOI 10.1016/j.cbpb.2018.06.004.

• Features and outcomes of drugs for combination therapy as multi-targets strategy to combat Alzheimer’s disease.

Sahoo, A.K., Dandapat, J., Dash, U.C. & Kanhar, S. Journal of Ethnopharmacology (2017); 215: pp.42-73.

• Neonatal Exposure to 6-n-Propyl-Thiouracil, an Anti-Thyroid Drug, Alters Expression of Hepatic DNA Methyltransferases, Methyl CpG-Binding Proteins, Gadd45a, p53, and PCNA in Adult Male Rats.

Bunker, S.K., Dandapat, J., Chainy, G.B., Sahoo, S.K. & Nayak, P.K. European Thyroid Journal. (2017); 6: pp.281-291.

• Differential expression of apoptotic proteins in seminiferous tubule cells of adult rats by neonatal exposure to 6-n-propyl-2-thiouracil (PTU), a thyroid disrupting chemical.

Sahoo, S.K., Dandapat, J., and Chainy, G.B.N. Indian Journal of Experimental Biology (2017); 55: pp.634-641.

• Curcumin and Ellagic acid synergistically induce ROS generation, DNA damage, p53 accumulation and apoptosis in HeLa cervical carcinoma cells.

Kumar, D., Basu, S., Parija, L., Rout, D., Manna, S., Dandapat, J., and Debata, P.R. Biomedicine & Pharmacotherapy. (2016); 81:  pp.31-37.

• An Overview of Seasonal Changes in Oxidative Stress and Antioxidant Defence Parameters in Some Invertebrate and Vertebrate Species.

Chainy, G.B.N., Paital, B. and Dandapat, J.(2016). Scientifica

• Homeopathic Medicine Rauwolfia serpentina Ameliorate Blood Pressure and Oxidative Stress Parameters of Kidney by Modulating Expression of Antioxidant Enzymes in Deoxycorticosterone Acetate (DOCA)-Salt-Induced Hypertensive Rat Model.

Kumar, S., Dandapat, J., Chainy, G.B.N., Hati, A.K. and Nanda, L. J Drug Res Dev. (2016); 2(1): pp.2470-1009.

• Neonatal persistant exposure to 6 propyl- 2 Thiouracil, A Thyroid disrupting chemical, differentially modulates expression of hepatic catalase and C/EBP-β in adult rats.

SK Bunker, J Dandapat, SK Sahoo, A Ray, GBN Chainy. Journal of Biochemical & Molecular Toxicology. (2015); DOI: 10.1002/jbt.21766.

• Hypothyroidism impairs antioxidant defence system and histoarchitecture of cerebral cortex of rat brain during postnatal development.

Srikanta Jena, Shravani Bhanja, Jagneshwar Dandapat, Gagan B.N. Chainy. Int. J. Devl Neuroscience 47. (2015);doi.org/10.1016/j.ijdevneu.2015.04.202.

• Pro-oxidative challenges and antioxidant protection during larval development of non-mulberry silkworm, Antheraea mylitta (Lepidoptera: Saturniidae).

A Sahoo, S Sahu, J Dandapat and L Samanta, Italian J of Zoology. (2015);doi: 10.1080/11250003.2015.1103319

• Age related decrease in rat liver catalase expression is associated with change in its promoter methylation pattern.

S.K. Bunker, J. Dandapat, G.B.N. Chainy. Current trends in Biotechnology and Pharmacy(2015); 9(1): 88-96.

• Foliar supplementation of zinc modulates growth and antioxidant defense system of tasar silkworm Antheraea mylitta.

Sahu, J. Dandpat, N. Mohanty, Journal of Entomology and Zoology Studies. (2015); 3(2):25-35.

• Oxidative Damaged products, Level of Hydrogen Peroxide and antioxidant protection in Diapausing Pupa of Tasar Silk Worm, Antherae amylitta: A Comparative Study in Two Voltine Groups.

A.Sahoo, J. Dandapat, L. Samanta. International journal of Insect Science. (2015); 7:11-17.

• Neonatal hypothyroidism alters expression of antioxidant enzymes and redox status in adult rat seminiferous tubule cells.

S.K. Sahoo, G.B.N. Chainy, J. Dandapat. Current trends in Biotechnology and Pharmacy. (2015); 9(2): 117-131.

• Effect of aminotriazole on antioxidant defense system of tasar silkworm Antheraea mylitta.

B Patra, S Sahu, J Dandapat. Entomological Science. (2014); 17: 316-323, doi:10.1111/ens.12060 .

• Effect of heavy metals on growth response and antioxidant defense protection in Bacillus cerus.

M Behera, J Dandapat, CC Rath. J of Basic Microbiol. (2014); 54: 1201-1209.

• PEGylation of an osteoclast inhibitory peptide: Suitable candidate for the treatment of osteoporosis.

J Akhtar, V Mallaredy, J Dandapat, P Maiti, SK Sahoo, and S Singh. International Journal of Pharmaceutics. (2012); 434: 429-436.

• Hypothyroidism modulates renal antioxidant gene expression during postnatal development and maturation in rat.

S Jena, GBN Chainy and J Dandapat. General and Comparative Endocrinology. (2012); 178: 8-18.

• Curcumin differentially regulates the expression of superoxide dismutase in cerebral cortex and cerebellum of L-thyroxine (T₄)-induced hyperthyroid rat brain.

S Jena, J Dandapat, and GBN Chainy. Neurological Sciences (2012); (DOI 10.1007/s10072-012-1084-z).

• Expression of antioxidant genes in renal cortex of PTU-induced hypothyroid rats: effect of vitamin E and curcumin.

S Jena, GBN Chainy, and J Dandapat. Molecular Biology Reports. (2012); 39 (2): 1193-1203.

• Induction of oxidative stress and inhibition of superoxide dismutase expression in rat cerebral cortex and cerebellum by PTU-induced hypothyroidism and its reversal by curcumin.

S Jena, C Anand, GBN Chainy and J Dandapat. Neurological Sciences.(2012); 33 (4): 869-873.

• Isolation and characterization and screening of bacteria isolate from Similipal Biosphere Reserve forest soil for their metal tolerance capacity and extracellular enzymatic activity.

Madhumita Behera, Jagneshwar Dandapat, Chandi C. Rath. Bioremediation, Biodiversity and Bioavailability. (2009); 3 (2): 72-78.

• Probiotic induced immunomodulation: Investigation into the cellular and Molecular mechanism involved.

Panigrahi, A., Azad, I. S., Das, B. K., Dandapat, J., Das, G., Behera, S. and Mishra, S.S. Research Journal of Biotechnology. (2009); 4(3):7-13.

• Lipid Peroxidation and nonenzymetic antioxidants, Glutathione and ascorbic acid, in a carp, Labio rohita.

Sahoo, M.Patra and J. Dandapat. Asian Journal of Microbiology Biotechnology and Environmental Science. (2008); 10 (127-130).

• Non-enzymatic antioxidant status and modulation of lipid peroxidation in the muscles of Labeo rohita by sub lethal exposure of CuSO4.

D. Jena & M. Behera & J. Dandapat & N. Mohanty. Vet Res Commun (2009); 33:421–429, DOI 10.1007/s11259-008-9188-x

• Lipid peroxidation and antioxidant defence status during larval development and metamorphosis of giant prawn, Macrobrachium rosenbergii.

Jagneshwar Dandapat, Gagan B.N. Chainy, K. Janardhana Rao. Comparative Biochemistry and Physiology Part C. (2003); 135: 221–233.

• Improved post larval production in Giant Prawn Macrobrachium rosenbergii through modulation of antioxidant defense system by Dietary Vitamin-E.

Jagneshwar Dandapat, GBN Chainy and K Janardhana Rao. Indian Journal Of Biotechnology. (2003);  2:195-202.

• Comparative evaluation of biochemical parameters in wild and cultured brood stock of Macrobrachium rosenbergii.

Bindu R. Pillai, A.P. Tripathy and J. Dandapat. Indian J. Fish. (2001); 48(1): 35-39.

• Dietary vitamin-E modulates antioxidant defence system ingiant freshwater prawn, Macrobrachium rosenbergii.

Jagneshwar Dandapat, Gagan B.N. Chainy, K. Janardhana Rao. Comparative Biochemistry and Physiology Part C. (2000); 127: 101–115.

• Antioxidant defence system in giant prawn Macrobrachium rosenbergii.

Jagneswar Dandapat, Gagan B.N. Chainy. (2001), http://hdl.handle.net/10603/227825

• An in vitro study of metal ion-induced lipid peroxidation in giantfresh water prawn Macrobrachium rosenbergii (de MAN).

Jagneswar Dandapat, K. Janardhana Rao & Gagan B.N. Chainy. BioMetals. (1999); 12: 89–97.

Referred Conference Publications

1. Abinash Dutta, J Dandapat, (2018) Oxidative stress in tasarsilk worm Antheraea mylitta: Beneficial role of antioxidant for improvement of larval health and silk production. National Seminar on Recent trends in Microbiology and Biotechnology, organized by the Society of Biotechnology and Bioinformatics and MITS school of Biotechnology, Bhubaneswar, Odisha from 16^th-17^th March, 2018

2. Sandeep Kumar, A.K Hati, G.B.N Chainy, L.K Nanda, J Dandapat. Effect of Homeopathic medicine Rauwolfia serpentina on expression of superoxide dismutase in heart of Deoxycorticosterone acetate (DOCA)- salt induced hypertensive rat. National Seminar on Recent trends in Microbiology and Biotechnology, organized by the Society of Biotechnology and Bioinformatics and MITS school of Biotechnology, Bhubaneswar, Odisha from 16^th-17^th March, 2018

3. SmaranikaSahu, J. Dandapat, N.M Effect of Manganese on growth and anti oxidantdefence of Antheraea mylitta National Seminar on Recent trends in Microbiology and Biotechnology, organized by the Society of Biotechnology and Bioinformatics and MITS school of Biotechnology, Bhubaneswar, Odisha from 16^th-17^th March, 2018
4. Anita Roy & J. Dandapat (2014) Long term curcumin treatment modulates p53 expression in testis of hypothyroid rats. in International symposium on genetic analysis: translational and developmental & Annual meeting of Society of Biotechnologist (India), November 21-23, 2014
5. Anita Roy & J. Dandapat (2014). Persistent curcumin treatment ameliorates 4-Hydroxynonenal (4HNE) induced protein carbonylation in neonatal hypothyroid rat testis. In: 83^rd annual meeting of Society of Biological Chemists (INDIA) Evolution: Molecules to life December 18-21, 2014
6. Anita Roy & J. Dandapat (2014) Curcumin failed to modulate altered oxidative stress marker in PTU induced neonatal hypothyroid rat testis. In: National conference on current trends in life science research and challenges ahead. 28^th feb-2^nd March, 2014, Sambalpur University, Sambalpur.
7. Anita Roy & J. Dandapat (2014) Neonatal hypothyroidism induces serum 4-hydroxy-2-nonenal (4-HNE), a bioactive oxidative stress marker, in male rats and its regulation by curcumin. In: National symposium on emerging trends in Biotechnology: present scenario and future dimensions. 29^th-30^th March, 2014, Utkal University, Bhubaneswar.

10. Suresh Kumar Bunker, G. B. N. Chainy, J. Dandapat.(2014). “Comparative study of methylation pattern of catalase promoter in liver, kidney and cerebral cortex tissues of male rats during aging.” National symposium on Emerging trends in Biotechnology: Present scenario and future dimensions. March 29 ^th-30^th, 2014. Organized by P.G. Department of Biotechnology, Utkal University, Bhubaneswar, Odisha.
11. Suresh Kumar Bunker, G. B. N. Chainy, J. Dandapat (2014) “PTU induced Neonatal Hypothyroidism Modulates Methylation Pattern of Catalase Promoter in Rat Liver”. International Symposium on Genetic Analysis Translational and Developmental and Annual Meeting of Society for Biotechnologists (India). November 21^st to 23^rd, 2014. Organized by Department of Zoology, University Of Burdwan.
12. B. N. Chainy, Suresh Kumar Bunker, J. Dandapat (2014). “Down regulation of hepatic catalase in PTU- induced hypothyroid rats is due to promoter methylation. 84^th Annual Session of the National Academy of Sciences, India. 04-06 December, 2014. Organized by Jai Narayan Vyas University, Jodhpur (B/85/2014).
13. Suresh Kumar Bunker, G. B. N. Chainy, J. Dandapat “Neonatal  Persistant Hypothyroidism Modulates Rat Hepatic DNA Methyltransferase 3b (DNMT 3b) Expression in Adulthood”. 83^rd Annual Meeting of the Society of Biological Chemist of India. 17-21 December 2014. Organized By KIIT University Bhubaneswar, Institute of Life Sciences, Bhubaneswar and NISER Bhubaneswar.
14. Kumar, A. K. Hati, G. B. N. Chainy, L.K. Nanda, J. Dandapat (2014).“Effect of homoeopathic preparations of Rauwolfia serpentine ondeoxycorticosterone acetate (DOCA)-salt induced hypertensive rats” National Conference on Ethnopharmacology and Biotechnology in Drug Development: Prospects and Challenges. November 2014. Organized by Bundelkhand University, Jhansi and Society for Ethnopharmacology, India.
15. Sandeep Kumar, Akshaya Kumar Hati, JagneshwarDandapat, Gagan B. N. Chainy, Laxmikanta Nanda Effect of homoeopathic preparations of Rauwolfia serpentine on deoxycorticosterone acetate (DOCA)-salt induced hypertensive rats. National Conference on Current trends in Life sciences research and challenges ahead. Organized by School of Life sciences, Sambalpur University, Sambalpur.
16. Sahu, A. Dutta, J. Dandapat, N. Mohanty (2014). Effect of micronutrients on growth response and antioxidant defense system of silkworm Antheraea mylitta. National Conference on Current trends in Life sciences research and challenges ahead. Organized by School of Life sciences, Sambalpur University, Sambalpur.
17. Sandeep Kumar, Akshaya Kumar Hati, Jagneshwar Dandapat, Gagan B. N. Chainy, Laxmikanta Nanda (2014) “Expression of antioxidant enzymes in cardiac tissue of deoxycorticosterone acetate (DOCA)-salt induced hypertensive rat: Effect of homoeopathic preparations of Rauwolfia serpentina.” National symposium on Emerging trends in Biotechnology: Present scenario and future dimensions. March 29 ^th-30^th, 2014. Organized by P.G. Department of Biotechnology, Utkal University, Bhubaneswar, Odisha.
18. Sandeep Kumar, Akshaya Kumar Hati, G. B. N. Chainy, Laxmikanta Nanda, Jagneshwar Dandapat (2014) “Modulation of rat kidney SOD expression by homoeopathic preparations of Rauwolfia serpentine on deoxycorticosterone acetate (DOCA)-salt-induced hypertensive rats.”83^rd Annual Meeting of the Society of Biological Chemist of India. 17-21 December 2014. Organized By KIIT University Bhubaneswar, Institute of Life Sciences, Bhubaneswar and NISER Bhubaneswar.
19. Sahoo, J. Dandapat, G.B.N. Chainy (2014) “Alteration of Bax expression in seminiferous tubule cella of neonatal hypothyroid wisar rats.” 83^rd Annual Meeting of the Society of Biological Chemist of India. 17-21 December 2014. Organized By KIIT University Bhubaneswar, Institute of Life Sciences, Bhubaneswar and NISER Bhubaneswar.
20. Sahu, A. Dutta, J. Dandapat, N. Mohanty (2014). “Selenium modulates antioxidant defense response in the mid gut tissues of 5th instar larvae of Antheraea mylitta.” National seminar Organized by Department of Zoology, North Orissa University.
21. Jena, B Patra, S. Sah, J. Dandapat, GBN Chainy (2014) “Curcumin ameliorates oxidative stress without modulating the expressions of antioxidant enzymes in 6-n-propylthiouracil (PTU)-induced hypothyroid rat testes.” National symposium on Emerging trends in Biotechnology: Present scenario and future dimensions. March 29 ^th-30^th, 2014. Organized by P.G. Department of Biotechnology, Utkal University, Bhubaneswar, Odisha.
22. Sahoo, S. Sahu, A. Dutta, J. Dandapat, L. Samanta (2014) “Tissue and sex specific redox status and antioxidant defenses during pupal diapause of Antheraea mylitta.” National symposium on Emerging trends in Biotechnology: Present scenario and future dimensions. March 29 ^th-30^th, 2014. Organized by P.G. Department of Biotechnology, Utkal University, Bhubaneswar, Odisha.
23. Dutta, S. Sahu, I. Das, A. Datey, J. Dandapat (2014). “Immune response and antioxidant defense status in the larvae of tasar silk worm, Antheraea mylitta D. challenged with Escherichia coli”. International Symposium on Genetic Analysis: Translational and Developmental & Annual Meeting of Society for Biotechnologists (India). November 21-23, 2014. Organized by Department of Zoology, The University of Burdawn.
24. R. Debata, D. Kumar, D. Rout, P.K. Nayak, J. Dandapat.(2014). “Curcumin and Ellagic Acid synergistically induce p53 accumulation and apoptosis in HeLa cervical carcinoma cells.” International Symposium on Genetic Analysis: Translational and Developmental & Annual Meeting of Society for Biotechnologists (India). November 21-23, 2014. Organized by Department of Zoology, The University of Burdawn.
25. Suresh K Bunker, U Subudhi, J Dandapat, G.B.N. Chainy. (2013). “DNA methylation pattern of rat liver catalase promoter is modified by aging and neonatal Hypothyroidism”. Frist International and Third National Conference on Biotechnology, Bioinformatics and Bioengineering. June 28-29 2013. Organized by Society for Applied Biotechnology (India), Sri Venkateswara University, Tirupati, Andhra Pradesh India. Pp 46.
26. Suresh K Bunker, U Subudhi, J Dandapat, G.B.N. Chainy. (2013) “Aging Modulates methylation pattern of catalase promoter of rat liver”. National Conference on Emerging Trends and Challenges in Basic and Translational Research in Biochemistry. February 4-5, 2013. Organized by Under the auspices of Centre of Advanced Study, Department of Zoology, Banaras Hindu University, Varanasi UP India.
27. Sahoo, S. Sahu, J. Dandapat and L. Samanta (2013) Oxidative damaged products, Level of Hydrogen Peroxide and Antioxidant protection in Diapausing pupa of tasar silkworm, Antheraea mylitta: A comparative study in two voltine groups. National Symposium on recent advances in beneficial insects. November 27-29, 2013. Organized by Indian Institute of Natural Resins and Gums (IINRG) and SANRAG, Ranchi.
28. Dutta, S. Sahu, J. Dandapat and N. Mohanty (2013) Foliar supplementation of ascorbic acid and Glycine modulate antioxidant defence components in the larvae of tasar silkworm, Antheraea mylitta. National Symposium on recent advances in beneficial insects. November 27-29, 2013. Organized by Indian Institute of Natural Resins and Gums (IINRG) and SANRAG, Ranchi.

• Popular science articles on “Horseshoe crab” in two Oriya dailies, The Dharitri and The Sambad.
• Life cycle of Macrobrachiumrosenbergii

Pillai, B.R. and Dandapat, J.

• Training manual on Breeding and Hatchery Management of Macrobrachium rosenbergii, pp. 6-7, 6th-15th October 1998, organised by CIFA.
• Hatchery Technology of Macrobrachium rosenbergii

Rao, K.J., Pillai, Bindu. R., Sinha, M.K. Tripathy, A.P. and Dandapat, J.

• Training manual on Breeding and hatchery Management of Macrobrachium rosenbergii, pp. 8-12, 6th-15th October 1998, organised by CIFA.
• Role of Vitamins and Minerals in Prawn Aquaculture (Training manual on Breeding and Hatchery Management of Macrobrachium rosenbergii, pp. 24-29, 6th-15th October 1998, organised by CIFA) Dandapat, J. and Das, A.
• Baigyanik Prathayee Galda Chingdir Chas (Scientific prawn culture – A technical book in Bengali language). Dandapat, J., Sinha, M.K., Dutta, T. and Rao, K.J. 2000, CIFA–ICAR.

Mentoring of Ph.D Students:

                    12 (awarded)

• Mr. Javed Akthar:

Title:-Peptides and Mimetics as inhibitors of NF-kB pathway.

• Miss Alpana Sahoo:

Title:-Antioxidant defence status in Tasar Silkworm, Antheraea mylitta.

• Miss Madhumita Behera:

Title:-Studies on Soil bacteria and their Bioactive substances from Similipal Biosphere reserve.

• Miss Smaranika Sahu :

Title:-Cellular redox status during development of Antheraea mylitta under different physiological conditions.

• Mr. Sunil Kumar Sahoo:

Title:-Age related changes in the expression of antioxidant enzymes and apoptotic proteins in testis of neonatal hypothyroid rats.

• Mr. Suresh Kumar Bunker:

Title:-Effect of 6-n-Propyl-2-thiouracil, a thyroid disrupting drug, on Male rat liver: A study on catalase and DNA binding proteins.

• Mr. Abinash Dutta:

Title:-Redox regulatory mechanism in tasar Silkworm, Antheraea mylitta: Modulatory effect of exogenous antioxidants.

• Mr. Asit Ray:

Title:-Chemotyping, genotyping and neural network based modeling for drug yield optimization in Hedychium coronarium

• Dr. Sandeep Saini:

Title:-Validation of antihypertensive homeopathic drug Rauwolfia serpentina by biochemical and molecular approaches in rat model.

• Dr. Manas Kumar Jagdev:

Title:- Structural Characterization of Mycobacterial and Plant Clp Chaperone Machinery Proteins

• Dr. Atala Bihari Jena

Title:- Conformational dynamics of biomolecules exposed to polycyclic aromatic hydrocarbon.

• Dr. Umesh Chandra Dash

Title:- Pharmacological Profiling of Geophila repens and Piper trioicum and Evaluation of Their Therapeutic Potential Against Alzheimer’s diseases.

No of ongoing Ph.D Scholars –

• Jyoti Prava Jema Topic: “Understanding the redox status and DNA Methylation machinery associated with hypothyroidism and possible intervention by Homeopathic Drug” (ongoing)
• Namrata Kanungo Topic: “Status of NLRP3 inflammasome in hypothyroidism-induced rat brain: Implications of epigenetic regulation and impact of curcumin and n-3 fatty acids (ongoing)
• Madhusmita Sahoo Topic: “Neonatal Thyroid Disruption-Associated Inflammaging in Rat: Implications of “NLRP3 Inflammasome & DNA Methylation” and Impact of Curcumin.” (ongoing)
• Subham Saraswata Jyotirmaya Topic: “Implication of DNA Methylation on redox driven cardiovascular dysfunction and efficacy of phytocompounds for adjunct therapy”(ongoing)

Mentoring of Post Doctoral Students:

• Anita Roy, Post-Doctoral candidate, (Utkal University) – Project entitled “4-HNE Mediated signalling in hypothyroidism induced male infertility; role of GST and modulation by Curcumin”

2012-2015.(completed)

• Priya Ranjan Debata as Ramalingamswami fellow (Utkal University), Project entitled“To characterize a novel topical cream based cream therapy against cervical cancer and targeting cervical cancer by modulating the tumor microenvironment” (Completed)
• Madhusmita Nayak, Post-Doctoral candidate, (Utkal University),“Project entitled “Neonatal hypothyroidism-induced epigenetic plasticity in the brain of adult rat: Implications of DNA methylation machinery and impact of Curcumin” (Completed)
• Suvasmita Rath, Post-Doctoral candidate, (Utkal University), Project entitled “Epigenetic regulation of HIF-1α expression and therapeutic interventions by bioactive compounds during cellular senescence” (ongoing).

Mentoring of M.Phil Students and Research Scholar:

• Jyoti Prava Jema, Research Scholar, (Utkal University) –Efficacy of Homeopathic Drug (30C) in PTU-induced Hypothyroid rat. (Since 2020) (Ongoing Project)
• Deepak Panda, Research Scholar, (Utkal University) –Efficacy of Homeopathic Drug (30C) in PTU-induced Hypothyroid rat.(2021-22)
• Nitish Kumar Bhol, Research Scholar, (Utkal University) –“Signature of DNA methylation machinery in the brain of propyl thiouracil (PTU)-induced hypothyroid rat: Effect of green tea catechins” funded by DST, Govt. of Odisha(PI) (2018-2021) (Completed)
• Rupali Rajeswari, M.Phil. Student , (Utkal University) (completed)
• Diptimayee Gochhi, M.Phil. Student , (Utkal University) (completed)
• Subham Saraswata Jyotirmaya, M.Phil. Student , (Utkal University) (completed)
• Madhusmita Sahoo, M.Phil. Student , (Utkal University) (completed)

• Collaborative Research Project Grant in Biotechnology, DST Govt. of Odisha, (PI) “Understanding the molecular mechanism of anti thyroid drug (propylthiouracil)-induced redox imbalance and epigenetic alteration” (2023-2026)
• Project entitled “Efficacy of Homeopathic Drug (30C) in PTU-induced Hypothyroid rat” funded by AYUSH, Govt. of India (PI) (Since 2020)
• Project entitled “Signature of DNA methylation machinery in the brain of propyl thiouracil (PTU)-induced hypothyroid rat: Effect of green tea catechins” funded by DST, Govt. of Odisha(PI) (2018-2021) (Completed)

1. International Symposium on Genomics in Aquaculture, “Beyond genomics: Epigenomic in aquaculture and the way forward”, organized by the ICAR-Central institute of fresh water Aquaculture in collaboration with association of Aquaculturists during 21^st-23^rd February, 2020.
2. National Conference on Biotechnology: Prospective and Challenges, “Remodeling Redox  Regulatory  Network In  Silk Worm : Insights  From  Proteomics And  Systems  Biology”Organized by Department of Biotechnology, under quality improvement programme, Savitribai Phule University, Puneduring 14^th-15^th February, 2020.
3. Annual Meeting of the Society for Free Radical Research. India & Conference on “Role and Management of Oxidative stress in Human Disease” (SFRR-INDIA-2020), “Hepatic epigenetic changes in the adult male rats under altered thyroid state: Impact of natural antioxidant curcumin” Organized by Bio-Science group, Bhaba Atomic Research Centre, Mumbai during 12^th-13^th February, 2020.
4. Oxidative stress induced in rat brain by altered thyroid hormone titer is rescued by curcumin. Resource person in NeuroScience International Conference on Translational Neuroscience & Its Application in protection of Mental Health. in XXXV Annual Meeting of Indian Academy of neuroscience  organized by Ravenshaw University  on 29-31, Oct., 2017.
5. Proteomics in the era of Omics. Resource person in National Seminar on Emerging trends in Biotechnology and crop improvements organized by Department of Biotechnology, Rama Devi Women’s University, Bhubaneswar, Odisha, India from 21st to 22nd November, 2017.
6. Redox homeostasis: a cross talk between oxidative defenses and immune response. UGC Sponsored National Seminar on current approaches in life Science. M.P.C. Autonomous College, Baripada, 21-22 March, 2015.
7. PTU induced Neonatal Hypothyroidism Modulates Methylation Pattern of Catalase Promoter in Rat Liver. Symposium Lecture in the International Symposium on Genetic Analysis Translational and Developmental and Annual Meeting of Society for Biotechnologists (India). Organized by Department of Zoology, The University Of Burdwan on November 21^st to 23^rd, 2014.
8. Exciting World of Biology. Invited talk in the inspire programme cum Residential Science camp for School and College students. Organised by Vidyasagar University and sponsored by Dept of Science and Technology, Govt. Of India and Govt. Of West Bengal on June 26, 2014.
9. Oxidative challenges and antioxidant protection in aquatic organisms: from biomarkers to health management. Invited lecture in the International Symposium on Problem and prospects of coastal aquaculture and application of biotechnological tool for the rural development. Organised by Vidhasagar University, sponsored by DBT, Govt of India, UGC, New Delhi on March 1-3, 2013.
10. DNA methylation and histone modification: Impact on Epigenetics. Delivered lecture in the National workshop on Hands on DNA technologies. Nagarjuna Post graduate College of Science, Raipur sponsored by UGC, New Delhi on January 8-11, 2013.
11. Biofertilizers. Invited Talk in the National Seminar on sustainable development through the use of Biofertilizers. AUL College, sponsored by UGC, New Delhi on January 5-6, 2013.
12. Organic Farming. Invited talk in the State level seminar on Biotechnology and Organic Farming. Dept of Botany, Balikuda College, Jagatsinghpur, sponsored by UGC, New Delhi on March 4-5, 2012.
13. Body’s Battle. Delivered lecture in the Science Seminar. Gopabandhu Science College, Athagarh on February 8, 2012.
14. Ameliorative Effect of Curcumin on the expression of Superoxide dismutase and level of Lipid Peroxidation in cerebral cortex of hypo and hyperthyroid rats. Delivered talk in the International conference on Biotechnology Advances: OMICS, Appraches and way forward. SOA University, Bhubaneswar on December 20-22, 2012.
15. Defence system of the Body. Delivered lecture in the Seminar organized by Science Society. Seemanta Mahavidyalaya, Jharpokhria on February 19, 2011.
16. Insect Diapause: Can hydrogen peroxide be a potent regulator. Invited lecture in the Regional Biochemical Symposium organised by Society of Biological chemistry, India and NISER, Bhubaneswar on September 3, 2011.
17. Invited lecture in the International Level Seminar on Problems and Prospects of Coastal Aquaculture and Application of Biotechnological Tools For Rural Development organized by Department of Aquaculture Management & Technology, Vidyasagar University, Midnapore, West Bengal, India from 1^st – 3^rd March,2013.
18. Participated in 99^th Indian science Congress on Science and Technology for Inclusive Innovation: Role of Women organized by KIIT and NISER, Bhubaneswar from 3^rd January 2012 to & 7^th January 2012.
19. Participated in 1^st meeting of Indian Immunological Society-Odisha Chapter organized by NISER and ILS, Bhubaneswar, Odisha on August 11, 2012.
20. Participated in XXXV All India Cell Biology Conference (AICB) & Symposium on Membrane dynamics and Disease organized by NISER, Bhubaneswar from 16^th-18^th December 2011.
21. Participated in International Brainstorming meet 2011 on Recent Advances in Fish Reproductive Physiology organized by CIFA, Kausalyaganga, Bhubaneswar on 16.08.2011.
22. Participated in ICAR, New Delhi sponsored Winter School on Recent Advances in Fish & Shell fish Immunology and its application organized by CIFA, Kausalyaganga, Bhubaneswar from 21.10.2008 to 10.11.2008.
23. Idea generation workshop in Aquaculture Biotechnology during 26-27 September, 2007 organised by Central Institute of Freshwater Aquaculture, Bhubaneswar and sponsored by Department of Biotechnology, Government of India.
24. Participated in a training programme on “Molecular techniques in Animal disease diagnosis” organized by National Biotechnology Centre, Indian Veterinary Research Institute, Izat Nagar, Bareli from 09th March to 29th March, 2004.
25. Participated in a short term training course cum workshop on “Electrophoresis Techniques” held in the Electrophoresis Institute, Yercaud, Tamilnadu from 27.05.2002 to 01.06.2002.
26. Undergone a training programme on “Breeding and Hatchery Management of Carps” in Central Institute of Freshwater Aquaculture (ICAR), Kausalyaganga, Bhubaneswar from 06.06.2000 to 14.6.2000.
27. Undergone a training programme on “Reproductive Physiology of Carp and Catfishes” in Central Institute of Freshwater Aquaculture (ICAR), Kausalyaganga, Bhubaneswar, from 27th July to 1^st August, 1998.
28. Undergone a training programme on “Aquatic Microbiology” in Central Institute of Freshwater Aquaculture (ICAR), Kausalyaganga, Bhubaneswar, from 17th May to 23rd May, 1994.

• Post Doctoral Fellowship sponsored by of Biotechnology, Govt. of India by selection committee for DBT-Post Doctoral Fellowship held in Indian Institute of Science, Bangalore in 2002.
• Orissa Young Scientist Award for the year 1999 from Department of Science & Technology, Govt. of Orissa for significant contribution in the field of Life Sciences.
• Best paper (poster) presentation award from Indian Science Congress Association in 86th Indian Science Congress held at Chennai in January 1999.
• Best research scholar award for the year 1998 in Central Institute of Freshwater Aquaculture (ICAR), Kausalyaganga, Bhubaneswar.
• National Scholarship received from of India for studying M.Sc. in the year 1990.

• Participated in DST sponsored workshop on Basic and Advanced proteomic Approaches organized by IIT Bombay from 15 – 26 February, 2021.
• Participated in ICAR, New Delhi sponsored Winter School on Recent Advances in Fish & Shell fish Immunology and its application organized by CIFA, Kausalyaganga, Bhubaneswar from 21.10.2008 to 10.11.2008.
• Idea generation workshop in Aquaculture Biotechnology during 26-27 September, 2007 organised by Central Institute of Freshwater Aquaculture, Bhubaneswar and sponsored by Department of Biotechnology, Government of India.
• Participated in a training programme on “Molecular techniques in Animal disease diagnosis” organized by National Biotechnology Centre, Indian Veterinary Research Institute, Izat Nagar, Bareli from 09th March to 29th March, 2004.
• Participated in a short-term training course cum workshop on “Electrophoresis Techniques” held in the Electrophoresis Institute, Yercaud, Tamil Nadu from 27.05.2002 to 01.06.2002.
• Undergone a training programme on “Breeding and Hatchery Management of Carps” in Central Institute of Freshwater Aquaculture (ICAR), Kausalyaganga, Bhubaneswar from 06.06.2000 to 14.6.2000.
• Undergone a training programme on “Reproductive Physiology of Carp and Catfishes” in Central Institute of Freshwater Aquaculture (ICAR), Kausalyaganga, Bhubaneswar, from 27th July to 1st August, 1998.
• Undergone a training programme on “Aquatic Microbiology” in Central Institute of Freshwater Aquaculture (ICAR), Kausalyaganga, Bhubaneswar, from 17th May to 23rd May, 1994.

Members in Academic Committees and Policy making bodies

1. Member- Advisory committee DBT- Star College Programme, Salepur College, Odisha
2. Executive council member, Odisha Bigyan Academy, Govt. of Odisha from 2018.
3. Chairman- Board of studies in Biotechnology, Utkal University, Bhubaneswar, 2010 – 2017
4. Member-Academic Council- Utkal University, Bhubaneswar 2010–2017, since 2019
5. Member-Subject Research Committee, Biotechnology, Utkal University since 2010 and Chairman, subject research committee, Biotechnology, Since 2017
6. Member-Academic Committee, Institute of Life Sciences, Bhubaneswar (2010-2011)
7. Member-Task force committee on Biotechnology, DST, Govt. of Odisha, 2013
8. Member-Committee for setting up of Biotechnology Incubation Center in Konark Knowledge Park, DST, Govt. of Odisha
9. Member-Biosafety Committee Central Rice Research Institute, Cuttack as DBT-Govt. of India nominee
10. Member- Advisory committee DBT-Star College Programme, N.L. Khan College, Midnapur, West Bengal
11. Member-Board of Studies in Zoology and Life Sciences, Utkal University
12. Member-Board of Studies in Biotechnology, Ravenshaw University (2010-2011)
13. Member-Board of Studies in Biotechnology, North Orissa University, Baripada (Since 2011)

Administrative / Executive experience:

1. Officer on Special Duty, New Campus, Utkal University (April 2018-February 2021)
2. Overall administration of the Department as Head from 2010-2017 and since 2019.
3. Course Coordinator for M.Sc. Biotechnology programme supported by DBT, Govt. of India under DBT-HRD programme from 2010-2017 and since 2019
4. Executive member of Odisha Bigyan Academy, DST, Government of Odisha from 2018
5. Coordinator, Centre of Excellence in integrated OMICs and Computational Biology from 2018
6. Coordinator, Platinum Jubilee distinguished Lecture Series, Utkal university
7. Other administrative responsibilities as assigned by University Authority from time to time

Patents / Product Commercialisation

Contributed for “Formulation and Commercialization of indigenous feed for different life stages of freshwater prawn” developed at Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar.

Contributed for development of anti-transferrin antibody and commercialization of the product by Abgenexindia ltd.

Reviewer

• Reviewer of various peer reviewed journals from Elsevier, Springer, Wiley, RSC Advance.

Conferences organized as Organizing Secretary:

• National Symposium on Emerging trends in Biotechnology : Present scenario and future dimensions on 29^th and 30^th March, 2014.
• UGC-sponsored skill development work shop on “Determination of protein content in biological sample” 19^th and 20^th November, 2015.

Professional Membership

• Life member of “The Indian Science Congress Association”.
• Life Member of “Association of Gerontology, India”.
• Life Member of “Biotechnology Society of India”
• Life Member of “Indian society of cell Biology”
• Life Member of “Society for free radical Research India”
• Life Member of “Society of Biological chemists India”
• Life member of “Association of Aquaculturist”, Kausalyaganga, Bhubaneswar, India.